adduser domain1
addgroup domain1
adduser www-data domain1
mkdir -p /home/domain1
chown domain1:domain1 -R /home/domain1
chmod 750 -R /home/domain1

adduser domain2
addgroup domain2
adduser www-data domain2
mkdir -p /home/domain2
chown domain2:domain2 -R /home/domain2
chmod 750 -R /home/domain2

nano /etc/lighttpd.conf

$HTTP["host"] == "domain1.com" {
server.document-root = "/home/domain1"
accesslog.filename = "/var/log/lighttpd/domain1/access.log"
}

$HTTP["host"] == "domain2.com" {
server.document-root = "/home/domain2"
accesslog.filename = "/var/log/lighttpd/domain2/access.log"
}

/etc/init.d/lighttpd restart